Cargando…
Hsp70 Interacts with the TREM-1 Receptor Expressed on Monocytes and Thereby Stimulates Generation of Cytotoxic Lymphocytes Active against MHC-Negative Tumor Cells
The search for and analysis of new ligands for innate immunity receptors are of special significance for understanding the regulatory mechanisms of immune response. Here we show that the major heat shock protein 70 (Hsp70) can bind to and activate TREM-1, the innate immunity receptor expressed on mo...
Autores principales: | Sharapova, Tatiana N., Romanova, Elena A., Ivanova, Olga K., Yashin, Denis V., Sashchenko, Lidia P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267615/ https://www.ncbi.nlm.nih.gov/pubmed/34206968 http://dx.doi.org/10.3390/ijms22136889 |
Ejemplares similares
-
N-Terminal Peptide of PGLYRP1/Tag7 Is a Novel Ligand for TREM-1 Receptor
por: Sharapova, Tatiana N., et al.
Publicado: (2022) -
Cytokines TNFα, IFNγ and IL-2 Are Responsible for Signal Transmission from the Innate Immunity Protein Tag7 (PGLYRP1) to Cytotoxic Effector Lymphocytes
por: Sharapova, Tatiana N., et al.
Publicado: (2020) -
A 12-mer Peptide of Tag7 (PGLYRP1) Forms a Cytotoxic Complex with Hsp70 and Inhibits TNF-Alpha Induced Cell Death
por: Romanova, Elena A., et al.
Publicado: (2020) -
Incubation of Lymphocytes with IL-2 Causes the Appearance of Antitumor T Cells Carrying FC, CD25, and LFA-1 on the Surface
por: Ivanova, O. K., et al.
Publicado: (2023) -
Tag7-Mts1 Complex Induces Lymphocytes Migration via CCR5 and CXCR3 Receptors
por: Sharapova, T. N., et al.
Publicado: (2018)