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NecroX-5 Can Suppress Melanoma Metastasis by Reducing the Expression of Rho-Family GTPases

NecroX-5 (NX-5) is a cell-permeable necrosis inhibitor with cytoprotective effects. Although it has been reported to inhibit lung and breast cancer metastasis by modulating migration, its therapeutic effect on melanoma metastasis is still unknown. In this study, we examined the anti-metastatic effec...

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Detalles Bibliográficos
Autores principales: Moon, Gue-Tae, Lee, Ji-Hyun, Jeong, Sang-Hyun, Jin, Song-Wan, Park, Young-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267632/
https://www.ncbi.nlm.nih.gov/pubmed/34201921
http://dx.doi.org/10.3390/jcm10132790