Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Protect Cardiomyocytes from Doxorubicin-Induced Cardiomyopathy by Upregulating Survivin Expression via the miR-199a-3p-Akt-Sp1/p53 Signaling Pathway

Cardiotoxicity is associated with the long-term clinical application of doxorubicin (DOX) in cancer patients. Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEVs) including exosomes have been suggested for the treatment of various diseases, including ischemic diseases. However, the...

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Detalles Bibliográficos
Autores principales: Lee, Ji Yoon, Chung, Jihwa, Byun, Yeongju, Kim, Kyoung Hwa, An, Shung Hyun, Kwon, Kihwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267634/
https://www.ncbi.nlm.nih.gov/pubmed/34281156
http://dx.doi.org/10.3390/ijms22137102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267634/
https://www.ncbi.nlm.nih.gov/pubmed/34281156
http://dx.doi.org/10.3390/ijms22137102

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