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Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Protect Cardiomyocytes from Doxorubicin-Induced Cardiomyopathy by Upregulating Survivin Expression via the miR-199a-3p-Akt-Sp1/p53 Signaling Pathway
Cardiotoxicity is associated with the long-term clinical application of doxorubicin (DOX) in cancer patients. Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEVs) including exosomes have been suggested for the treatment of various diseases, including ischemic diseases. However, the...
Autores principales: | Lee, Ji Yoon, Chung, Jihwa, Byun, Yeongju, Kim, Kyoung Hwa, An, Shung Hyun, Kwon, Kihwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267634/ https://www.ncbi.nlm.nih.gov/pubmed/34281156 http://dx.doi.org/10.3390/ijms22137102 |
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