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Enhanced NAMPT-Mediated NAD Salvage Pathway Contributes to Psoriasis Pathogenesis by Amplifying Epithelial Auto-Inflammatory Circuits

Dysregulated cross-talk between immune cells and epithelial compartments is responsible for the onset and amplification of pathogenic auto-inflammatory circuits occurring in psoriasis. NAMPT-mediated NAD salvage pathway has been recently described as an immunometabolic route having inflammatory func...

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Detalles Bibliográficos
Autores principales: Mercurio, Laura, Morelli, Martina, Scarponi, Claudia, Scaglione, Giovanni Luca, Pallotta, Sabatino, Avitabile, Daniele, Albanesi, Cristina, Madonna, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267663/
https://www.ncbi.nlm.nih.gov/pubmed/34202251
http://dx.doi.org/10.3390/ijms22136860