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Midazolam’s Effects on Delayed-Rectifier K(+) Current and Intermediate-Conductance Ca(2+)-Activated K(+) Channel in Jurkat T-lymphocytes

Midazolam (MDZ) could affect lymphocyte immune functions. However, the influence of MDZ on cell’s K(+) currents has never been investigated. Thus, in the present study, the effects of MDZ on Jurkat T lymphocytes were studied using the patch-clamp technique. Results showed that MDZ suppressed the amp...

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Detalles Bibliográficos
Autores principales: Foo, Ning-Ping, Liu, Yu-Fan, Wu, Ping-Ching, Hsing, Chung-Hsi, Huang, Bu-Miin, So, Edmund-Cheung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267671/
https://www.ncbi.nlm.nih.gov/pubmed/34281255
http://dx.doi.org/10.3390/ijms22137198