Cargando…

Midazolam’s Effects on Delayed-Rectifier K(+) Current and Intermediate-Conductance Ca(2+)-Activated K(+) Channel in Jurkat T-lymphocytes

Midazolam (MDZ) could affect lymphocyte immune functions. However, the influence of MDZ on cell’s K(+) currents has never been investigated. Thus, in the present study, the effects of MDZ on Jurkat T lymphocytes were studied using the patch-clamp technique. Results showed that MDZ suppressed the amp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Foo, Ning-Ping, Liu, Yu-Fan, Wu, Ping-Ching, Hsing, Chung-Hsi, Huang, Bu-Miin, So, Edmund-Cheung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267671/ https://www.ncbi.nlm.nih.gov/pubmed/34281255 http://dx.doi.org/10.3390/ijms22137198

Ejemplares similares

Actions of FTY720 (Fingolimod), a Sphingosine-1-Phosphate Receptor Modulator, on Delayed-Rectifier K(+) Current and Intermediate-Conductance Ca(2+)-Activated K(+) Channel in Jurkat T-Lymphocytes
por: Chang, Wei-Ting, et al.
Publicado: (2020)

High Effectiveness in Actions of Carfilzomib on Delayed-Rectifier K(+) Current and on Spontaneous Action Potentials
por: So, Edmund Cheung, et al.
Publicado: (2019)

Fast Inactivation of Delayed Rectifier K Conductance in Squid Giant Axon and Its Cell Bodies
por: Mathes, Chris, et al.
Publicado: (1997)

Pimozide Increases a Delayed Rectifier K(+) Conductance in Chicken Embryo Vestibular Hair Cells
por: Giunta, Roberta, et al.
Publicado: (2023)

Cancer-Associated Intermediate Conductance Ca(2+)-Activated K(+) Channel K(Ca)3.1
por: Mohr, Corinna J., et al.
Publicado: (2019)

Carboxy-terminal Determinants of Conductance in Inward-rectifier K Channels
por: Zhang, Yu-Yang, et al.
Publicado: (2004)

Midazolam inhibits chondrogenesis via peripheral benzodiazepine receptor in human mesenchymal stem cells
por: Chen, Yung‐Ching, et al.
Publicado: (2018)

Rectifying conductance substates in a large conductance Ca(2+)- activated K+ channel: evidence for a fluctuating barrier mechanism
Publicado: (1996)

Conduction through a narrow inward-rectifier K(+) channel pore
por: Bernsteiner, Harald, et al.
Publicado: (2019)

Ginseng Gintonin Activates the Human Cardiac Delayed Rectifier K(+) Channel: Involvement of Ca(2+)/Calmodulin Binding Sites
por: Choi, Sun-Hye, et al.
Publicado: (2014)

Intermediate-Conductance-Ca2-Activated K Channel Intermediate-Conductance Calcium-Activated Potassium Channel (IKCa1) is Upregulated and Promotes Cell Proliferation in Cervical Cancer
por: Liu, Ling, et al.
Publicado: (2017)

Membrane-delimited Inhibition of Maxi-K Channel Activity by the Intermediate Conductance Ca(2+)-activated K Channel
por: Thompson, Jill, et al.
Publicado: (2006)

External K(+) dependence of strong inward rectifier K(+) channel conductance is caused not by K(+) but by competitive pore blockade by external Na(+)
por: Ishihara, Keiko
Publicado: (2018)

Effect of sodium ferulate on delayed rectifier K(+) currents in PC12 cells
por: WANG, WEI, et al.
Publicado: (2014)

Structure, Gating and Basic Functions of the Ca(2+)-activated K Channel of Intermediate Conductance
por: Sforna, Luigi, et al.
Publicado: (2018)

Editorial The Role of Ca(2+)-activated K(+) Channels of Intermediate Conductance in Glioblastoma Malignancy
por: Catacuzzeno, Luigi, et al.
Publicado: (2018)

Differential effects of ginsenoside metabolites on slowly activating delayed rectifier K(+ )and KCNQ1 K(+) channel currents
por: Choi, Sun-Hye, et al.
Publicado: (2013)

Bisoprolol, Known to Be a Selective β(1)-Receptor Antagonist, Differentially but Directly Suppresses I(K(M)) and I(K(erg)) in Pituitary Cells and Hippocampal Neurons
por: So, Edmund Cheung, et al.
Publicado: (2019)

Inward Rectifier K(+) Currents Are Regulated by CaMKII in Endothelial Cells of Primarily Cultured Bovine Pulmonary Arteries
por: Qu, Lihui, et al.
Publicado: (2015)

Intermediate Conductance Ca(2+)-Activated K(+) Channels Modulate Human Placental Trophoblast Syncytialization
por: Díaz, Paula, et al.
Publicado: (2014)

Mechanism of Rectification in Inward-rectifier K(+) Channels
por: Guo, Donglin, et al.
Publicado: (2003)

The GPR55 agonist lysophosphatidylinositol directly activates intermediate-conductance Ca(2+)-activated K(+) channels
por: Bondarenko, Alexander I., et al.
Publicado: (2011)

Arylbenzazepines Are Potent Modulators for the Delayed Rectifier K(+) Channel: A Potential Mechanism for Their Neuroprotective Effects
por: Chen, Xue-Qin, et al.
Publicado: (2009)

Ultrarapid Delayed Rectifier K(+) Channelopathies in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Hilderink, Sarah, et al.
Publicado: (2020)

Activation of the Ca(2+)-sensing receptors increases currents through inward rectifier K(+) channels via activation of phosphatidylinositol 4-kinase
por: Liu, Chung-Hung, et al.
Publicado: (2016)

Upregulation of an inward rectifying K(+) channel can rescue slow Ca(2+) oscillations in K(ATP) channel deficient pancreatic islets
por: Yildirim, Vehpi, et al.
Publicado: (2017)

The Polyamine Binding Site in Inward Rectifier K(+) Channels
por: Kurata, Harley T., et al.
Publicado: (2006)

Alteration of the transmembrane K+ gradient during development of delayed rectifier in isolated rat pulmonary arterial cells
Publicado: (1994)

Permeation of Na+ through a delayed rectifier K+ channel in chick dorsal root ganglion neurons
Publicado: (1994)

Forskolin Suppresses Delayed-Rectifier K(+) Currents and Enhances Spike Frequency-Dependent Adaptation of Sympathetic Neurons
por: Angel-Chavez, Luis I., et al.
Publicado: (2015)

Role of the rapid delayed rectifier K(+) current in human induced pluripotent stem cells derived cardiomyocytes
por: Deo, Makarand, et al.
Publicado: (2020)

Anticancer Effects of Midazolam on Lung and Breast Cancers by Inhibiting Cell Proliferation and Epithelial-Mesenchymal Transition
por: Lu, Hsin-Ling, et al.
Publicado: (2021)

Gating and Inward Rectifying Properties of the MthK K(+) Channel with and without the Gating Ring
por: Li, Yang, et al.
Publicado: (2007)

Interactions of external K(+) and internal blockers in a weak inward-rectifier K(+) channel
por: Yang, Lei, et al.
Publicado: (2012)

Characterization and Chemical Synthesis of Cm39 (α-KTx 4.8): A Scorpion Toxin That Inhibits Voltage-Gated K(+) Channel K(V)1.2 and Small- and Intermediate-Conductance Ca(2+)-Activated K(+) Channels K(Ca)2.2 and K(Ca)3.1
por: Naseem, Muhammad Umair, et al.
Publicado: (2023)

Midazolam induces apoptosis in MA-10 mouse Leydig tumor cells through caspase activation and the involvement of MAPK signaling pathway
por: So, Edmund Cheung, et al.
Publicado: (2014)

Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents
Publicado: (1990)

Delayed rectifying and calcium-activated K+ channels and their significance for action potential repolarization in mouse pancreatic beta-cells
Publicado: (1990)

Physiological Roles of the Rapidly Activated Delayed Rectifier K(+) Current in Adult Mouse Heart Primary Pacemaker Activity
por: Hu, Wei, et al.
Publicado: (2021)

Human Sinoatrial Node Pacemaker Activity: Role of the Slow Component of the Delayed Rectifier K(+) Current, I(Ks)
por: Verkerk, Arie O., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s7nidou1favhhlhi7669ipegoq