Prevalence of DNA Repair Gene Mutations in Blood and Tumor Tissue and Impact on Prognosis and Treatment in HNSCC

SIMPLE SUMMARY: The DNA damage repair (DDR) gene profile is largely unexplored in head and neck squamous cell cancer (HNSCC), leaving little known about the treatment of HNSCC with PARP inhibitors. In this retrospective study, the prevalence of mutated DDR genes was studied in the tissue and/or bloo...

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Detalles Bibliográficos
Autores principales: Burcher, Kimberly M., Faucheux, Andrew T., Lantz, Jeffrey W., Wilson, Harper L., Abreu, Arianne, Salafian, Kiarash, Patel, Manisha J., Song, Alexander H., Petro, Robin M., Lycan, Thomas, Furdui, Cristina M., Topaloglu, Umit, D’Agostino, Ralph B., Zhang, Wei, Porosnicu, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267691/
https://www.ncbi.nlm.nih.gov/pubmed/34206538
http://dx.doi.org/10.3390/cancers13133118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267691/
https://www.ncbi.nlm.nih.gov/pubmed/34206538
http://dx.doi.org/10.3390/cancers13133118

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