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Identification of the Merkel Cell Polyomavirus Large Tumor Antigen Ubiquitin Conjugation Residue

Merkel cell polyomavirus (MCPyV) large tumor (LT) antigen is a DNA binding protein essential for viral gene transcription and genome replication. MCPyV LT interacts with multiple E3 ligases in a phosphorylation-dependent manner, limiting its own viral replication by enhancing LT protein degradation,...

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Detalles Bibliográficos
Autores principales: Ortiz, Luz E., Pham, Alexander M., Kwun, Hyun Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267701/
https://www.ncbi.nlm.nih.gov/pubmed/34281220
http://dx.doi.org/10.3390/ijms22137169