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Selective Antitumor Activity of Datelliptium toward Medullary Thyroid Carcinoma by Downregulating RET Transcriptional Activity

SIMPLE SUMMARY: Medullary thyroid carcinoma (MTC) is a rare aggressive type of thyroid cancer with a propensity for metastasizing to the lymph nodes, liver, bones, and lungs. Previous studies have demonstrated that activated REarranged during Transfection (RET) mutants are key regulators of invasive...

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Detalles Bibliográficos
Autores principales: Alqahtani, Tariq, Alswied, Abdullah, Sun, Daekyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267783/
https://www.ncbi.nlm.nih.gov/pubmed/34209165
http://dx.doi.org/10.3390/cancers13133288