Zn-Enhanced Asp-Rich Antimicrobial Peptides: N-Terminal Coordination by Zn(II) and Cu(II), Which Distinguishes Cu(II) Binding to Different Peptides

The antimicrobial activity of surfactant-associated anionic peptides (SAAPs), which are isolated from the ovine pulmonary surfactant and are selective against the ovine pathogen Mannheimia haemolytica, is strongly enhanced in the presence of Zn(II) ions. Both calorimetry and ITC measurements show th...

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Detalles Bibliográficos
Autores principales: Miller, Adriana, Matera-Witkiewicz, Agnieszka, Mikołajczyk, Aleksandra, Wątły, Joanna, Wilcox, Dean, Witkowska, Danuta, Rowińska-Żyrek, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267837/
https://www.ncbi.nlm.nih.gov/pubmed/34203496
http://dx.doi.org/10.3390/ijms22136971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267837/
https://www.ncbi.nlm.nih.gov/pubmed/34203496
http://dx.doi.org/10.3390/ijms22136971

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