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Disruption of O-Linked N-Acetylglucosamine Signaling in Placenta Induces Insulin Sensitivity in Female Offspring

Placental dysfunction can lead to fetal growth restriction which is associated with perinatal morbidity and mortality. Fetal growth restriction increases the risk of obesity and diabetes later in life. Placental O-GlcNAc transferase (OGT) has been identified as a marker and a mediator of placental i...

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Detalles Bibliográficos
Autores principales: Moore, Mackenzie, Avula, Nandini, Jo, Seokwon, Beetch, Megan, Alejandro, Emilyn U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267851/
https://www.ncbi.nlm.nih.gov/pubmed/34203166
http://dx.doi.org/10.3390/ijms22136918