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Transcriptional Profiling of Monocytes Deficient in Nuclear Orphan Receptors NR4A2 and NR4A3 Reveals Distinct Signalling Roles Related to Antigen Presentation and Viral Response

The nuclear receptor sub-family 4 group A (NR4A) family are early response genes that encode proteins that are activated in several tissues/cells in response to a variety of stressors. The NR4A family comprises NR4A1, NR4A2 and NR4A3 of which NR4A2 and NR4A3 are under researched and less understood,...

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Detalles Bibliográficos
Autores principales: Phelan, David E., Shigemura, Masahiko, Aldhafiri, Sarah, Mota, Catarina, Hall, Thomas J., Sznajder, Jacob I., Murphy, Evelyn P., Crean, Daniel, Cummins, Eoin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267906/
https://www.ncbi.nlm.nih.gov/pubmed/34248958
http://dx.doi.org/10.3389/fimmu.2021.676644