Design, Synthesis, In Silico and In Vitro Studies for New Nitric Oxide-Releasing Indomethacin Derivatives with 1,3,4-Oxadiazole-2-thiol Scaffold

Starting from indomethacin (IND), one of the most prescribed non-steroidal anti-inflammatory drugs (NSAIDs), new nitric oxide-releasing indomethacin derivatives with 1,3,4-oxadiazole-2-thiol scaffold (NO-IND-OXDs, 8a–p) have been developed as a safer and more efficient multitarget therapeutic strate...

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Detalles Bibliográficos
Autores principales: Sava, Alexandru, Buron, Frederic, Routier, Sylvain, Panainte, Alina, Bibire, Nela, Constantin, Sandra Mădălina, Lupașcu, Florentina Geanina, Focșa, Alin Viorel, Profire, Lenuţa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267937/
https://www.ncbi.nlm.nih.gov/pubmed/34209248
http://dx.doi.org/10.3390/ijms22137079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267937/
https://www.ncbi.nlm.nih.gov/pubmed/34209248
http://dx.doi.org/10.3390/ijms22137079

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