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Hepatic Branch Vagotomy Modulates the Gut-Liver-Brain Axis in Murine Cirrhosis

BACKGROUND: Cirrhosis and hepatic encephalopathy (HE) are linked with an altered gut-liver-brain axis, however, the relative contribution of hepatic vagal innervation is unclear. We aimed to determine the impact of hepatic vagotomy on the gut microbiome, brain, and liver in murine cirrhosis. METHODS...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Kang, Jason D., Zhao, Derrick, Ghosh, Siddartha S., Wang, Yanyan, Tai, Yunling, Gonzalez-Maeso, Javier, Sikaroodi, Masoumeh, Gillevet, Patrick M., Lippman, H. Robert, Hylemon, Phillip B., Zhou, Huiping, Bajaj, Jasmohan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268007/
https://www.ncbi.nlm.nih.gov/pubmed/34248683
http://dx.doi.org/10.3389/fphys.2021.702646