CD3G or CD3D Knockdown in Mature, but Not Immature, T Lymphocytes Similarly Cripples the Human TCRαβ Complex

The human αβ T-cell receptor (TCR) is composed of a variable heterodimer (TCRαβ) and three invariant dimers (CD3γε, CD3δε, and ζζ/CD247(2)). The role of each invariant chain in the stepwise interactions among TCR chains along the assembly is still not fully understood. Despite the high sequence homo...

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Detalles Bibliográficos
Autores principales: Garcillán, Beatriz, Fuentes, Patricia, Marin, Ana V., Megino, Rebeca F., Chacon-Arguedas, Daniel, Mazariegos, Marina S., Jiménez-Reinoso, Anaïs, Muñoz-Ruiz, Miguel, Laborda, Raquel G., Cárdenas, Paula P., Fernández-Malavé, Edgar, Toribio, Maria L., Regueiro, José R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268008/
https://www.ncbi.nlm.nih.gov/pubmed/34249896
http://dx.doi.org/10.3389/fcell.2021.608490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268008/
https://www.ncbi.nlm.nih.gov/pubmed/34249896
http://dx.doi.org/10.3389/fcell.2021.608490

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