The Effect of Fluid Flow Shear Stress and Substrate Stiffness on Yes-Associated Protein (YAP) Activity and Osteogenesis in Murine Osteosarcoma Cells

SIMPLE SUMMARY: Primary bone cancers like osteosarcoma (OS) are driven by bone cells that develop mutations, and behave in an uncontrolled manner. All bone cells, including defective ones, are sensitive to their physical environment. We tested the response of osteosarcoma cells, at the gene level, t...

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Detalles Bibliográficos
Autores principales: Coughlin, Thomas R., Sana, Ali, Voss, Kevin, Gadi, Abhilash, Basu-Roy, Upal, Curtin, Caroline M., Mansukhani, Alka, Kennedy, Oran D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268052/
https://www.ncbi.nlm.nih.gov/pubmed/34201496
http://dx.doi.org/10.3390/cancers13133128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268052/
https://www.ncbi.nlm.nih.gov/pubmed/34201496
http://dx.doi.org/10.3390/cancers13133128

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