Chitinases and Chitinase-Like Proteins as Therapeutic Targets in Inflammatory Diseases, with a Special Focus on Inflammatory Bowel Diseases

Chitinases belong to the evolutionarily conserved glycosyl hydrolase family 18 (GH18). They catalyze degradation of chitin to N-acetylglucosamine by hydrolysis of the β-(1-4)-glycosidic bonds. Although mammals do not synthesize chitin, they possess two enzymatically active chitinases, i.e., chitotri...

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Detalles Bibliográficos
Autores principales: Mazur, Marzena, Zielińska, Anna, Grzybowski, Marcin M., Olczak, Jacek, Fichna, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268069/
https://www.ncbi.nlm.nih.gov/pubmed/34203467
http://dx.doi.org/10.3390/ijms22136966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268069/
https://www.ncbi.nlm.nih.gov/pubmed/34203467
http://dx.doi.org/10.3390/ijms22136966

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