Cargando…

Nonameric Peptide Orchestrates Signal Transduction in the Activating HLA-E/NKG2C/CD94 Immune Complex as Revealed by All-Atom Simulations

The innate immune system’s natural killer (NK) cells exert their cytolytic function against a variety of pathological challenges, including tumors and virally infected cells. Their activation depends on net signaling mediated via inhibitory and activating receptors that interact with specific ligand...

Descripción completa

Detalles Bibliográficos
Autores principales: Prašnikar, Eva, Perdih, Andrej, Borišek, Jure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268078/
https://www.ncbi.nlm.nih.gov/pubmed/34206395
http://dx.doi.org/10.3390/ijms22136670