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Nonameric Peptide Orchestrates Signal Transduction in the Activating HLA-E/NKG2C/CD94 Immune Complex as Revealed by All-Atom Simulations

The innate immune system’s natural killer (NK) cells exert their cytolytic function against a variety of pathological challenges, including tumors and virally infected cells. Their activation depends on net signaling mediated via inhibitory and activating receptors that interact with specific ligand...

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Detalles Bibliográficos
Autores principales: Prašnikar, Eva, Perdih, Andrej, Borišek, Jure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268078/
https://www.ncbi.nlm.nih.gov/pubmed/34206395
http://dx.doi.org/10.3390/ijms22136670

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