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DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer’s Disease

DNA repair ensures genomic stability to achieve healthy ageing, including cognitive maintenance. Mutations on genes encoding key DNA repair proteins can lead to diseases with accelerated ageing phenotypes. Some of these diseases are xeroderma pigmentosum group A (XPA, caused by mutation of XPA), Coc...

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Detalles Bibliográficos
Autores principales: Wang, Heling, Lautrup, Sofie, Caponio, Domenica, Zhang, Jianying, Fang, Evandro F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268089/
https://www.ncbi.nlm.nih.gov/pubmed/34201700
http://dx.doi.org/10.3390/ijms22136748