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Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is an extremely lethal cancer with very limited therapeutic options. Cancer stem cells (CSCs) are essential for propagation of PDAC, but also for its metastatic activity and chemoresistance. To date, it is still unclear how cancer stem cells (C...

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Detalles Bibliográficos
Autores principales: Walter, Karolin, Rodriguez-Aznar, Eva, Ferreira, Monica S. Ventura, Frappart, Pierre-Olivier, Dittrich, Tabea, Tiwary, Kanishka, Meessen, Sabine, Lerma, Laura, Daiss, Nora, Schulte, Lucas-Alexander, Najafova, Zeynab, Arnold, Frank, Usachov, Valentyn, Azoitei, Ninel, Erkan, Mert, Lechel, Andre, Brümmendorf, Tim H., Seufferlein, Thomas, Kleger, Alexander, Tabarés, Enrique, Günes, Cagatay, Johnsen, Steven A., Beier, Fabian, Sainz, Bruno, Hermann, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268125/
https://www.ncbi.nlm.nih.gov/pubmed/34201898
http://dx.doi.org/10.3390/cancers13133145