Hydrogen Bonds, Topologies, Energy Frameworks and Solubilities of Five Sorafenib Salts

Sorafenib (Sor) is an oral multi-kinase inhibitor, but its water solubility is very low. To improve its solubility, sorafenib hydrochloride hydrate, sorafenib hydrobromide and sorafenib hydrobromide hydrate were prepared in the mixed solvent of the corresponding acid solution, and tetrahydrofuran (T...

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Detalles Bibliográficos
Autores principales: Phan, Chiuyen, Shen, Jie, Yu, Kaxi, Liu, Jiyong, Tang, Guping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268146/
https://www.ncbi.nlm.nih.gov/pubmed/34206574
http://dx.doi.org/10.3390/ijms22136682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268146/
https://www.ncbi.nlm.nih.gov/pubmed/34206574
http://dx.doi.org/10.3390/ijms22136682

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