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Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG(2)T(G(3)T)(3)] and Its Derivatives with an Abasic Site Replacing Single Thymidine

In this paper, we report our investigations on five T30175 analogues, prepared by replacing sequence thymidines with abasic sites (S) one at a time, in comparison to their natural counterpart in order to evaluate their antiproliferative potential and the involvement of the residues not belonging to...

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Detalles Bibliográficos
Autores principales: Virgilio, Antonella, Benigno, Daniela, Pecoraro, Annalisa, Russo, Annapina, Russo, Giulia, Esposito, Veronica, Galeone, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268168/
https://www.ncbi.nlm.nih.gov/pubmed/34208896
http://dx.doi.org/10.3390/ijms22137040