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Pharmacokinetic evaluation of Chalcone derivatives with antimalarial activity in New Zealand White Rabbits
OBJECTIVE: Malaria is a major global health concern with the urgent need for new treatment alternatives due to the alarming increase of drug-resistant Plasmodium strains. Chalcones and its derivatives are important pharmacophores showing antimalarial activity. Determination of the pharmacokinetic va...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268181/ https://www.ncbi.nlm.nih.gov/pubmed/34238361 http://dx.doi.org/10.1186/s13104-021-05684-8 |