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Insights Into the Micelle-Induced β-Hairpin-to-α-Helix Transition of a LytA-Derived Peptide by Photo-CIDNP Spectroscopy

A choline-binding module from pneumococcal LytA autolysin, LytA(239–252,) was reported to have a highly stable nativelike β-hairpin in aqueous solution, which turns into a stable amphipathic α-helix in the presence of micelles. Here, we aim to obtain insights into this DPC-micelle triggered β-hairpi...

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Detalles Bibliográficos
Autores principales: Gomez, M. Victoria, Ruiz-Castañeda, Margarita, Nitschke, Philipp, Gschwind, Ruth M., Jiménez, M. Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268221/
https://www.ncbi.nlm.nih.gov/pubmed/34206372
http://dx.doi.org/10.3390/ijms22136666