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Studies of Conformational Changes of Tubulin Induced by Interaction with Kinesin Using Atomistic Molecular Dynamics Simulations

The transition between strong and weak interactions of the kinesin head with the microtubule, which is regulated by the change of the nucleotide state of the head, is indispensable for the processive motion of the kinesin molecular motor on the microtubule. Here, using all-atom molecular dynamics si...

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Detalles Bibliográficos
Autores principales: Shi, Xiao-Xuan, Wang, Peng-Ye, Chen, Hong, Xie, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268240/
https://www.ncbi.nlm.nih.gov/pubmed/34201478
http://dx.doi.org/10.3390/ijms22136709