Analyzing the Opportunities to Target DNA Double-Strand Breaks Repair and Replicative Stress Responses to Improve Therapeutic Index of Colorectal Cancer

SIMPLE SUMMARY: Colorectal cancer (CRC) is among the most common cancers and the third leading cause of cancer deaths worldwide. Despite the identification of alterations in DNA repair genes and the resulting genomic instability in sub-populations of CRC, therapies that exploit defects in DNA repair...

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Detalles Bibliográficos
Autores principales: Tomasini, Paula Pellenz, Guecheva, Temenouga Nikolova, Leguisamo, Natalia Motta, Péricart, Sarah, Brunac, Anne-Cécile, Hoffmann, Jean Sébastien, Saffi, Jenifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268241/
https://www.ncbi.nlm.nih.gov/pubmed/34201502
http://dx.doi.org/10.3390/cancers13133130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268241/
https://www.ncbi.nlm.nih.gov/pubmed/34201502
http://dx.doi.org/10.3390/cancers13133130

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