Regulation of ADAM10 by the TspanC8 Family of Tetraspanins and Their Therapeutic Potential

The ubiquitously expressed transmembrane protein a disintegrin and metalloproteinase 10 (ADAM10) functions as a “molecular scissor”, by cleaving the extracellular regions from its membrane protein substrates in a process termed ectodomain shedding. ADAM10 is known to have over 100 substrates includi...

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Detalles Bibliográficos
Autores principales: Harrison, Neale, Koo, Chek Ziu, Tomlinson, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268256/
https://www.ncbi.nlm.nih.gov/pubmed/34201472
http://dx.doi.org/10.3390/ijms22136707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268256/
https://www.ncbi.nlm.nih.gov/pubmed/34201472
http://dx.doi.org/10.3390/ijms22136707

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