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Regulation of ADAM10 by the TspanC8 Family of Tetraspanins and Their Therapeutic Potential
The ubiquitously expressed transmembrane protein a disintegrin and metalloproteinase 10 (ADAM10) functions as a “molecular scissor”, by cleaving the extracellular regions from its membrane protein substrates in a process termed ectodomain shedding. ADAM10 is known to have over 100 substrates includi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268256/ https://www.ncbi.nlm.nih.gov/pubmed/34201472 http://dx.doi.org/10.3390/ijms22136707 |