Curcumin Suppresses TGF-β1-Induced Myofibroblast Differentiation and Attenuates Angiogenic Activity of Orbital Fibroblasts

Orbital fibrosis, a hallmark of tissue remodeling in Graves’ ophthalmopathy (GO), is a chronic, progressive orbitopathy with few effective treatments. Orbital fibroblasts are effector cells, and transforming growth factor β1 (TGF-β1) acts as a critical inducer to promote myofibroblast differentiatio...

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Detalles Bibliográficos
Autores principales: Yu, Wei-Kuang, Hwang, Wei-Lun, Wang, Yi-Chuan, Tsai, Chieh-Chih, Wei, Yau-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268269/
https://www.ncbi.nlm.nih.gov/pubmed/34202024
http://dx.doi.org/10.3390/ijms22136829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268269/
https://www.ncbi.nlm.nih.gov/pubmed/34202024
http://dx.doi.org/10.3390/ijms22136829

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