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Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of Age-Related Macular Degeneration

Inflammation is a key underlying factor of age-related macular degeneration (AMD) and inflammasome activation has been linked to disease development. Induced pluripotent stem-cell-derived retinal pigment epithelial cells (iPSC-RPE) are an attractive novel model system that can help to further elucid...

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Detalles Bibliográficos
Autores principales: Hytti, Maria, Korhonen, Eveliina, Hongisto, Heidi, Kaarniranta, Kai, Skottman, Heli, Kauppinen, Anu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268331/
https://www.ncbi.nlm.nih.gov/pubmed/34202702
http://dx.doi.org/10.3390/ijms22136800