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Inference of kinase-signaling networks in human myeloid cell line models by Phosphoproteomics using kinase activity enrichment analysis (KAEA)

BACKGROUND: Despite the introduction of targeted therapies, most patients with myeloid malignancies will not be cured and progress. Genomics is useful to elucidate the mutational landscape but remains limited in the prediction of therapeutic outcome and identification of targets for resistance. Dysr...

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Detalles Bibliográficos
Autores principales: Hallal, Mahmoud, Braga-Lagache, Sophie, Jankovic, Jovana, Simillion, Cedric, Bruggmann, Rémy, Uldry, Anne-Christine, Allam, Ramanjaneyulu, Heller, Manfred, Bonadies, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268341/
https://www.ncbi.nlm.nih.gov/pubmed/34238254
http://dx.doi.org/10.1186/s12885-021-08479-z