Deciphering the Nature of Trp73 Isoforms in Mouse Embryonic Stem Cell Models: Generation of Isoform-Specific Deficient Cell Lines Using the CRISPR/Cas9 Gene Editing System

SIMPLE SUMMARY: The Trp73 gene is involved in the regulation of multiple biological processes such as response to stress, differentiation and tissue architecture. This gene gives rise to structurally different N and C-terminal isoforms which lead to differences in its biological activity in a cell t...

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Detalles Bibliográficos
Autores principales: López-Ferreras, Lorena, Martínez-García, Nicole, Maeso-Alonso, Laura, Martín-López, Marta, Díez-Matilla, Ángela, Villoch-Fernandez, Javier, Alonso-Olivares, Hugo, Marques, Margarita M., Marin, Maria C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268375/
https://www.ncbi.nlm.nih.gov/pubmed/34202306
http://dx.doi.org/10.3390/cancers13133182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268375/
https://www.ncbi.nlm.nih.gov/pubmed/34202306
http://dx.doi.org/10.3390/cancers13133182

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