Aη-α and Aη-β peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo

BACKGROUND: Amyloid precursor protein (APP) processing is central to Alzheimer’s disease (AD) etiology. As early cognitive alterations in AD are strongly correlated to abnormal information processing due to increasing synaptic impairment, it is crucial to characterize how peptides generated through...

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Detalles Bibliográficos
Autores principales: Mensch, Maria, Dunot, Jade, Yishan, Sandy M., Harris, Samuel S., Blistein, Aline, Avdiu, Alban, Pousinha, Paula A., Giudici, Camilla, Busche, Marc Aurel, Jedlicka, Peter, Willem, Michael, Marie, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268417/
https://www.ncbi.nlm.nih.gov/pubmed/34238366
http://dx.doi.org/10.1186/s13195-021-00860-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268417/
https://www.ncbi.nlm.nih.gov/pubmed/34238366
http://dx.doi.org/10.1186/s13195-021-00860-1

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