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Fibrin(ogen) as a Therapeutic Target: Opportunities and Challenges

Fibrinogen is one of the key molecular players in haemostasis. Thrombin-mediated release of fibrinopeptides from fibrinogen converts this soluble protein into a network of fibrin fibres that form a building block for blood clots. Thrombin-activated factor XIII further crosslinks the fibrin fibres an...

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Detalles Bibliográficos
Autores principales: Gaule, Thembaninkosi G., Ajjan, Ramzi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268464/
https://www.ncbi.nlm.nih.gov/pubmed/34203139
http://dx.doi.org/10.3390/ijms22136916