Cargando…
Fibrin(ogen) as a Therapeutic Target: Opportunities and Challenges
Fibrinogen is one of the key molecular players in haemostasis. Thrombin-mediated release of fibrinopeptides from fibrinogen converts this soluble protein into a network of fibrin fibres that form a building block for blood clots. Thrombin-activated factor XIII further crosslinks the fibrin fibres an...
Autores principales: | Gaule, Thembaninkosi G., Ajjan, Ramzi A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268464/ https://www.ncbi.nlm.nih.gov/pubmed/34203139 http://dx.doi.org/10.3390/ijms22136916 |
Ejemplares similares
-
The role of fibrinogen, fibrin and fibrin(ogen) degradation products (FDPs) in tumor progression
por: Kołodziejczyk, Joanna, et al.
Publicado: (2013) -
Fibrin(ogen) in human disease: both friend and foe
por: Vilar, Rui, et al.
Publicado: (2020) -
Thrombin–Fibrin(ogen) Interactions, Host Defense and Risk of Thrombosis
por: Hulshof, Anne-Marije, et al.
Publicado: (2021) -
Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation
por: Page, Martin J., et al.
Publicado: (2019) -
Fibrin(ogen) mediates acute inflammatory responses to biomaterials
Publicado: (1993)