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Prolyl Carboxypeptidase Mediates the C-Terminal Cleavage of (Pyr)-Apelin-13 in Human Umbilical Vein and Aortic Endothelial Cells

The aim of this study was to investigate the C-terminal cleavage of (pyr)-apelin-13 in human endothelial cells with respect to the role and subcellular location of prolyl carboxypeptidase (PRCP). Human umbilical vein and aortic endothelial cells, pre-treated with prolyl carboxypeptidase-inhibitor co...

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Detalles Bibliográficos
Autores principales: De Hert, Emilie, Bracke, An, Pintelon, Isabel, Janssens, Eline, Lambeir, Anne-Marie, Van Der Veken, Pieter, De Meester, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268575/
https://www.ncbi.nlm.nih.gov/pubmed/34206648
http://dx.doi.org/10.3390/ijms22136698