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Ferryl Hemoglobin and Heme Induce A(1)-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation

Infiltration of red blood cells into atheromatous plaques and oxidation of hemoglobin (Hb) and lipoproteins are implicated in the pathogenesis of atherosclerosis. α(1)-microglobulin (A1M) is a radical-scavenging and heme-binding protein. In this work, we examined the origin and role of A1M in human...

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Detalles Bibliográficos
Autores principales: Pethő, Dávid, Gáll, Tamás, Hendrik, Zoltán, Nagy, Annamária, Beke, Lívia, Gergely, Attila Péter, Méhes, Gábor, Tóth, Csaba, Gram, Magnus, Åkerström, Bo, Balla, György, Balla, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268598/
https://www.ncbi.nlm.nih.gov/pubmed/34206377
http://dx.doi.org/10.3390/ijms22136668