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The Cerebral Effect of Ammonia in Brain Aging: Blood–Brain Barrier Breakdown, Mitochondrial Dysfunction, and Neuroinflammation

Aging occurs along with multiple pathological problems in various organs. The aged brain, especially, shows a reduction in brain mass, neuronal cell death, energy dysregulation, and memory loss. Brain aging is influenced by altered metabolites both in the systemic blood circulation and the central n...

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Detalles Bibliográficos
Autores principales: Jo, Danbi, Kim, Byeong C., Cho, Kyung A., Song, Juhyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268635/
https://www.ncbi.nlm.nih.gov/pubmed/34202669
http://dx.doi.org/10.3390/jcm10132773