Respective roles of Glycoprotein VI and FcγRIIA in the regulation of αIIbβ3‐mediated platelet activation to fibrinogen, thrombus buildup, and stability

BACKGROUND: The interplay between platelets and fibrinogen is the cornerstone of thrombus formation. Integrin αIIbβ3 is the main platelet adhesion receptor for fibrinogen and mediates an outside‐in signal upon ligand binding that reinforces platelet activation. In addition, FcγRIIA and glycoprotein...

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Detalles Bibliográficos
Autores principales: Ahmed, Muhammad Usman, Receveur, Nicolas, Janus‐Bell, Emily, Mouriaux, Clarisse, Gachet, Christian, Jandrot‐Perrus, Martine, Hechler, Béatrice, Gardiner, Elizabeth E., Mangin, Pierre H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268658/
https://www.ncbi.nlm.nih.gov/pubmed/34263103
http://dx.doi.org/10.1002/rth2.12551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268658/
https://www.ncbi.nlm.nih.gov/pubmed/34263103
http://dx.doi.org/10.1002/rth2.12551

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