DRP1 Inhibition Rescues Mitochondrial Integrity and Excessive Apoptosis in CS-A Disease Cell Models

Cockayne syndrome group A (CS-A) is a rare recessive progeroid disorder characterized by sun sensitivity and neurodevelopmental abnormalities. Cells derived from CS-A patients present as pathological hallmarks excessive oxidative stress, mitochondrial fragmentation and apoptosis associated with hype...

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Detalles Bibliográficos
Autores principales: Pascucci, Barbara, Spadaro, Francesca, Pietraforte, Donatella, Nuccio, Chiara De, Visentin, Sergio, Giglio, Paola, Dogliotti, Eugenia, D’Errico, Mariarosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268695/
https://www.ncbi.nlm.nih.gov/pubmed/34281194
http://dx.doi.org/10.3390/ijms22137123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268695/
https://www.ncbi.nlm.nih.gov/pubmed/34281194
http://dx.doi.org/10.3390/ijms22137123

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