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DRP1 Inhibition Rescues Mitochondrial Integrity and Excessive Apoptosis in CS-A Disease Cell Models

Cockayne syndrome group A (CS-A) is a rare recessive progeroid disorder characterized by sun sensitivity and neurodevelopmental abnormalities. Cells derived from CS-A patients present as pathological hallmarks excessive oxidative stress, mitochondrial fragmentation and apoptosis associated with hype...

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Detalles Bibliográficos
Autores principales:	Pascucci, Barbara, Spadaro, Francesca, Pietraforte, Donatella, Nuccio, Chiara De, Visentin, Sergio, Giglio, Paola, Dogliotti, Eugenia, D’Errico, Mariarosaria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268695/ https://www.ncbi.nlm.nih.gov/pubmed/34281194 http://dx.doi.org/10.3390/ijms22137123

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