Transamidation Down-Regulates Intestinal Immunity of Recombinant α-Gliadin in HLA-DQ8 Transgenic Mice

Enzymatic transamidation of gliadins by microbial transglutaminase (mTG) inhibits interferon-γ (IFN-γ) secretion by intestinal T cell lines in patients with celiac disease (CD). To gain insight into the cellular mechanisms underlying the down-regulatory effects of transamidation, we tested a single...

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Detalles Bibliográficos
Autores principales: Rossi, Stefano, Giordano, Deborah, Mazzeo, Maria Fiorella, Maurano, Francesco, Luongo, Diomira, Facchiano, Angelo, Siciliano, Rosa Anna, Rossi, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268696/
https://www.ncbi.nlm.nih.gov/pubmed/34209932
http://dx.doi.org/10.3390/ijms22137019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268696/
https://www.ncbi.nlm.nih.gov/pubmed/34209932
http://dx.doi.org/10.3390/ijms22137019

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