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Transamidation Down-Regulates Intestinal Immunity of Recombinant α-Gliadin in HLA-DQ8 Transgenic Mice
Enzymatic transamidation of gliadins by microbial transglutaminase (mTG) inhibits interferon-γ (IFN-γ) secretion by intestinal T cell lines in patients with celiac disease (CD). To gain insight into the cellular mechanisms underlying the down-regulatory effects of transamidation, we tested a single...
Autores principales: | Rossi, Stefano, Giordano, Deborah, Mazzeo, Maria Fiorella, Maurano, Francesco, Luongo, Diomira, Facchiano, Angelo, Siciliano, Rosa Anna, Rossi, Mauro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268696/ https://www.ncbi.nlm.nih.gov/pubmed/34209932 http://dx.doi.org/10.3390/ijms22137019 |
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