CDC2 Is an Important Driver of Vascular Smooth Muscle Cell Proliferation via FOXM1 and PLK1 in Pulmonary Arterial Hypertension

A key feature of pulmonary arterial hypertension (PAH) is the hyperplastic proliferation exhibited by the vascular smooth muscle cells from patients (HPASMC). The growth inducers FOXM1 and PLK1 are highly upregulated in these cells. The mechanism by which these two proteins direct aberrant growth in...

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Detalles Bibliográficos
Autores principales: Pal-Ghosh, Ruma, Xue, Danfeng, Warburton, Rod, Hill, Nicholas, Polgar, Peter, Wilson, Jamie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268698/
https://www.ncbi.nlm.nih.gov/pubmed/34203295
http://dx.doi.org/10.3390/ijms22136943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268698/
https://www.ncbi.nlm.nih.gov/pubmed/34203295
http://dx.doi.org/10.3390/ijms22136943

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