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RIP140 Represses Intestinal Paneth Cell Differentiation and Interplays with SOX9 Signaling in Colorectal Cancer

SIMPLE SUMMARY: In the small intestine, the transcription factor SOX9 regulates the differentiation of Paneth cells, which are key actors in the intestinal antimicrobial defense and stem cell niche. SOX9 is also an important player in colon cancer development and progression. In this study, we demon...

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Detalles Bibliográficos
Autores principales: Gleizes, Antoine, Triki, Mouna, Bonnet, Sandrine, Baccari, Naomi, Jimenez-Dominguez, Gabriel, Covinhes, Aurélie, Pirot, Nelly, Blache, Philippe, Yuan, Rong, Győrffy, Balázs, Cavaillès, Vincent, Lapierre, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268705/
https://www.ncbi.nlm.nih.gov/pubmed/34206767
http://dx.doi.org/10.3390/cancers13133192