Structural and Drug Targeting Insights on Mutant p53

SIMPLE SUMMARY: The tumor suppressor protein p53 is frequently mutated in human cancers, and its reactivation represents an encouraging hope for precision anticancer therapy. Despite this, the clinical use of compounds capable of restoring the wild-type-like function to mutant p53 (mutp53) is not ye...

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Detalles Bibliográficos
Autores principales: Gomes, Ana Sara, Ramos, Helena, Inga, Alberto, Sousa, Emília, Saraiva, Lucília
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268744/
https://www.ncbi.nlm.nih.gov/pubmed/34283062
http://dx.doi.org/10.3390/cancers13133344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268744/
https://www.ncbi.nlm.nih.gov/pubmed/34283062
http://dx.doi.org/10.3390/cancers13133344

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