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Structural and Drug Targeting Insights on Mutant p53
SIMPLE SUMMARY: The tumor suppressor protein p53 is frequently mutated in human cancers, and its reactivation represents an encouraging hope for precision anticancer therapy. Despite this, the clinical use of compounds capable of restoring the wild-type-like function to mutant p53 (mutp53) is not ye...
Autores principales: | Gomes, Ana Sara, Ramos, Helena, Inga, Alberto, Sousa, Emília, Saraiva, Lucília |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268744/ https://www.ncbi.nlm.nih.gov/pubmed/34283062 http://dx.doi.org/10.3390/cancers13133344 |
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