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A Novel Model for the RNase MRP-Induced Switch between the Formation of Different Forms of 5.8S rRNA

Processing of the RNA polymerase I pre-rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs requires removing the “spacer” sequences. The canonical pathway for the removal of the ITS1 spacer involves cleavages at the 3′ end of 18S rRNA and at two sites inside ITS1. The process can generate eithe...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Zengel, Janice M., Lindahl, Lasse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268776/
https://www.ncbi.nlm.nih.gov/pubmed/34206573
http://dx.doi.org/10.3390/ijms22136690